Once there is self, there is other.
From that, one becomes attached to the self and averse to other.
It is in connection with this
That all faults and problems arise.

Quote from the Pramanavartika, in Precious Teachings, by Khenpo Karten Rinpoche, page 42 in print version (48 in PDF version), “Essence of Buddhism as Related to the Four Noble Truths.” 

Image: Sphere of reflection by Ralph, AI Artist on Pixexid, creative commons, cropped.